A meta-analysis of an in vivo study also found that PVP-I may delay wound healing in the early stages of use, but as the overall total time for healing is not affected, the Wound Healing Society and the Japanese Pressure Ulcer Advisory Panel tend to allow the use of PVP-I. However, if an equilibrium is established in the composition, concentration and temperature of a povidone-free iodine composition, problems associated with skin exposure to early iodine components can be minimized. While 10% PVP-I is a commonly used antiseptic for infected wounds, it can inhibit the growth of new tissue when used on open wounds. However, since most antimicrobial dressings available in Korea are expensive imported silver dressings, less costly dressings containing antimicrobial agents such as povidone-iodine (PVP-I), an antiseptic that is commonly used in Korea, are needed. Therefore, if microorganisms colonize the wound or delay wound healing, antiseptics or antibacterial dressings should be used. In particular, infection should be suspected if the area where a PI frequently occurs is close to the perianal region or buttocks, where contamination from feces can repeatedly take place, and where there is always the potential to progress to an infection. As a result, biofilms can easily form on PIs and deteriorate into local infection or spread to become a systemic infection, so reducing the bacterial load is essential. On the other hand, chronic wounds such as PIs are very frequently colonized to a certain extent. Chronic wounds including PIs do not easily show symptoms of acute infection the symptoms are noted only when the infection is chronically advanced. Meanwhile, PIs are by definition ischemic areas that do not receive nutrition, oxygen, immune cells, antibodies or antibiotics normally, and are made more susceptible to infection by neurological disorders. Dressings of various materials are used for PI management to achieve these goals, among which polyurethane foam is particularly useful because it can absorb excess exudate and keep the PI area moist while reducing external pressure. For the treatment of PIs, it is most important to relieve pressure from the PI area, remove necrotic tissue to promote development of granulation tissue, and provide adequate hydration. Finally the highly breathable yet showerproof backing film enables longer wear time as well as protects the wound by stopping bacteria and viruses*. As the exudate reaches retention layer with superabsorbents its being effectively managed and retained which reduces the risk of leakage and maceration. Then the nonwoven spreading layer spreads exudate over a wide surface area within the retention layer. First the absorbent foam pad absorbs exudate and prevents it from returning to the wound, protecting the periwound skin. Mepilex Border can handle more exudate than other compared silicone foam dressings because of its unique material construction. Safetac interface also minimises damaging the wound or surrounding skin or exposing the patient to additional pain at dressing changes. The design includes a Safetac ® interface which seals the wound edges, preventing the exudate to leak onto the surrounding skin, thus minimising the risk for maceration. Mepilex Border is also clinically proven to help prevent pressure ulcers when used in conjunction with standard pressure ulcer prevention measures. The dressing is designed for a wide range of wounds such as pressure ulcers, leg and foot ulcers and traumatic wounds. Mepilex ® Border is a versatile five-layer all-in-one bordered foam dressing available in a large range of shapes and sizes.
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